Here comes our third video in the One Health Campaign 2017 series. In this video we will discuss what is antimicrobial resistance and what is multidrug resistant MDR.

https://www.youtube.com/watch?v=GpHQvEcsG8Y

What is antimicrobial resistant?

It looks simple to answer. Indeed antimicrobial resistant refers to an miroorganism showing resistant to an antimicrobial substance, which means this antimicrobial substance cannot control the growth of this microorganism. Often we are talking about an antimicrobial substance which is at first active against that microorganism but eventually become inactive, in other words, resistance. There are some we call intrinsic resistance which mean the microorganism is borne to have resistance to a particular antimicrobial substance. For example a erythromycin is useless on a E. coli bacteria. The explain more on the antimicrobial resistant, we can assume a E. coli bacteria which is at first be able to suppressed by a cephalosporin capsule, and when a resistance mechanism developed, this capsule is no longer useful and we describe this situation as "this E. coli is developed antimicrobial resistance to cephalosporin'. When this E. coli multiply (double in number every twenty minutes, generally speaking), all the 'offsprings' are also resistant to cephalosporin. At times when these offsprings E. coli develope antimicrobial resistance to another one, two or all antimicrobial substances we call this situation as multidrug resistance (MDR), and it is this MDR causing the global antimicribial problem which we are struggling to fight against. 

On the next episode we will talk about how a bacterial develope antimicrobial resistance.